Archive | Endometriosis

NEWS: Severe endometriosis adversely impacts outcomes of IVF therapy

Evidence regarding the impact of endometriosis on in vitro fertilization (IVF) therapy outcomes is controversial. A recent study, published in the British Journal of Obstetrics & Gynaecology, reports that women with stage III/IV endometriosis and undergoing IVF treatment experience poor rates of implantation and clinical pregnancy.
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Transabdominal Follicular Aspiration Effective for Oocyte Retrieval from Transvaginally Inaccessible Ovaries

A new retrospective case-control study has reported that oocyte retrieval via transabdominal ultrasound-guided follicular aspiration is safe and effective in IVF patients with substantial ovarian displacement, i.e. in cases where ovaries are inaccessible transvaginally. The study reported that the results were comparable to cycles where the oocytes were obtained by transvaginal aspiration in women with normally located ovaries. Continue Reading

Posted in ART, Diagnostics, Endometriosis, Equipments, Guidelines, ICSI, IVF, IVF Outcome, Infertility, TechnologyComments Off

Resection May Improve Fertility and Clinical Outcomes in Infertile Women with Bowel Endometriosis

Resection May Improve Fertility and Clinical Outcomes in Infertile Women with Bowel Endometriosis

A new study published in Reproductive BioMedicine Online reports improvement in pain symptoms, fertility outcomes, and overall patient satisfaction rates following surgical resection of bowel endometriosis in women with infertility. Continue Reading

Posted in ART, Endometriosis, Endometrium, Featured, Female Infertility, Fertility, IVF, Infertility, News, Reproductive SurgeryComments Off

Endometriosis and Infertility: Brief Review of Literature on Surgical Management Aspects

Introduction

Endometriosis, a common gynecological condition and a leading cause of infertility, affects around 2-10% of reproductive-aged women in the US, with a global prevalence of 0.5-5% and 25-40% in fertile and infertile women, respectively.1 Although most studies have established the association between endometriosis and infertility, there is a lack of sufficient understanding regarding a direct cause-and-effect link, particularly in early disease, when the pelvic anatomy is not disrupted. Hence, there also remains some ambiguity about the optimal management strategy for endometriosis-associated infertility. Continue Reading

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Altered Endometrial HOXA10 Gene Expression Linked to Infertility

A recent study reports that altered homeobox A10 (HOXA10) gene expression in the mid-secretory endometrium could play a role in infertility associated with endometriosis and uterine fibroids, as well as unexplained infertility. The findings, published in the recent issue of the journal Human Reproduction, suggest that the gene could be a potential target for new generation infertility treatments. Continue Reading

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Nerve Fiber Detection in Endometrial Biopsy Aids in Quick and Accurate Diagnosis of Endometriosis

Endometriosis, with a prevalence of 25-40% in infertile and 0.5-5% in fertile women, lacks a reliable and non-invasive test for its diagnosis, which results in an average delay of 6-10 years before confirmed diagnosis and treatment. A recent double blinded study has reported the efficacy of a test with high sensitivity and specificity for the diagnosis of endometriosis, which uses immunohistochemical techniques to detect nerve fibers in endometrial biopsy samples. The findings of the study, which claim that the endometrial biopsy probably has similar accuracy to laparoscopic assessment, have been published in the online edition of the journal, Human Reproduction. Continue Reading

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