Tag Archive | "Oocyte activation"

Researchers Identify Molecular Defect that Prevents Oocyte Activation

Several previous studies have tried to elucidate the complex signaling phenomenon underlying the mammalian oocytes activation. Intracellular Ca2+ oscillations triggered by the penetrated spermatozoa have been found to be crucial for both oocyte activation as well as normal embryo development. Now, a collaborative study conducted by US and UK researchers has reported that the abnormal expression of phospholipase Czeta 1 (PLCZ1) sperm protein is linked to the inability of the human sperm to induce Ca2+ oscillations, leading to failure of egg activation and sterility. Read the full story

Posted in ART, Embryology, Genetics, ICSI, IVF, Infertility, Male InfertilityComments (0)

Stay Updated via our Twitter Alerts!

Follow IVF NEWS.Direct! on Twitter